Human GITRL-TNF Superfamily -Cambridge Bio

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Human GITRL

Cat No.:    03-04-1360
Product Name:    Human GITRL
Size:    50 μg
Price:    $229

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Cat No.: 03-04-1360
Product Name: Human GITRL
Description: GITRL/TNFSF18 is a member of the tumor necrosis factor (TNF) superfamily which is a ligand for receptor TNFRSF18/AITR/GITR. it regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation
Type: Protein
Property: Protein
Source: HEK293
Genbank No.: Q9UNG2 ( aa.72-199)
Applications: WB,ELISA,Immunogen
Formulation: Each vial contains 50μg purified protein(1mg/ml) in PBS(pH7.4).
Purity: >95%
Storage: Store at -80°C,Avoid freeze / thaw cycle.
Limitation: For research use only,not for use in diagnostic procedures.
Reference: TNFSF18