Human PD-1-hIgG1-B7/CD28 Family-Cambridge Bio

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Human PD-1-hIgG1

Cat No.:    03-04-0079
Product Name:    Human PD-1-hIgG1
Size:    50 μg
Price:    $229

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Cat No.: 03-04-0079
Product Name: Human PD-1-hIgG1
Description: Programmed cell death protein 1, also known as PD-1 and CD279,functions as an immune checkpoint, plays an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance, by interaction with its ligands PD-L1/PD-L2 on APC/Treg (or cancer) cells. The inhibitory effect of PD-1 is accomplished through a dual mechanism of promoting apoptosis (programmed cell death) in antigen specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (suppressor T cells).
Type: Protein
Property: Protein
Source: HEK293
Genbank No.: Q15116 ( aa.21-170)
Applications: WB,ELISA,Immunogen
Formulation: Each vial contains 50μg purified protein(1mg/ml) in PBS(pH7.4).
Purity: >95%
Storage: Store at -80°C,Avoid freeze / thaw cycle.
Limitation: For research use only,not for use in diagnostic procedures.
Reference: CD279